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Modulation of metabolic detoxification pathways using foods and food-derived components: a scientific review with clinical application

It is especially crucial if cancer cells encounter scarce glucose but necessitates a signaling from lactic acid to facilitate the PPP

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Thus, much of the research in the field of exposure science examines exposures (toxicants) with previously known biologically active roles, such as reactive electrophiles, metabolites, metals, endocrine disruptors, persistent organic compounds, and modulators of immune responses (Rappaport and Smith, 2010)