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While environmental triggers (e.g., viral load, infections) play a major role, genetic predisposition often determines who escalates to a full cytokine storm versus those who mount a controlled response

- Requires complete and accurate documentation (labs such as serum ferritin and transferrin saturation/TSAT, diagnosis codes, prior oral-iron trial or intolerance) to support medical necessity and reimbursement

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It plays a critical role in neutralizing free radicals, recycling other antioxidants like vitamins C and E, and maintaining the bodys detoxification pathways