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Warnings: Patients with early Leber's disease (hereditary optic nerve atrophy) may experience severe and rapid optic atrophy when treated with vitamin B12. Additionally, treating severe megaloblastic anemia with vitamin B12 can lead to fatal hypokalemia due to increased erythrocyte potassium requirements

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[DOI] [PMC free article] [PubMed] [Google Scholar] 45.Chan W.K.B., Olson K.M., Wotring J.W., Sexton J.Z., Carlson H.A., Traynor J.R

Besides, the treatment improved the expressions of MMP-2 and MMP-9, TIMP-1 and TIMP-2 (tissue inhibitor of metalloproteinase) suggesting neuroprotection [50]

Environmental triggers and stress-related eating can also emerge once the initial pharmacological appetite suppression window closes

Oxidative stress increases with normal aging, and antioxidant support can support long-term wellness habits