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In turn, GSH increases the expression of CENPT, forming a CENPT-GCLC-GSH feedback loop to enhance the pro-carcinogenic effect of CENPT-GCLC-GSH axis on RCC

10.1021/ac302721j 207 YangY.ZhaiC.ZengQ.KhanA

However, the medication can cause psychiatric (related to mental illness) side effects

No statistical methods were used to pre-determine sample sizes, but our sample sizes are similar to those reported in previous publications 15,16

With GSH depleted, TCR signal transduction is blunted, reducing T-cell proliferation and protective cytokine output

In the CARES trial, remission rates reached 63.1% by year six, with over 59% of patients achieving remission at least once during the study period