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As telomeres shorten over time, cells may become senescent and lose their ability to divide

All patients were presented with ischemic stroke within 24 hours from symptom onset, and had relevant ischemic lesions on brain imaging

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Among 38 identified hits, we found a subset of chloroacetamides with broad senolytic activity

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The experimental groups were divided in N (water), C (30% alcohol), PJ (30% alcohol + 3% PJ powder), CM (30% alcohol + 3% CM powder), CM (30% alcohol + 3% CM powder) and SM [30% alcohol + 0.1% silymarin (SM)]