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Deubiquitination works with UPS to maintain protein homeostasis in organisms by affecting the level of ubiquitination of substrates and influencing the degradation of proteins by UPS

Greenhouse et al

For example, the report of palmitoyl carnitine elevation as an acylcarnitine increased in APAP toxicity in mice led to clinical studies to measure this and other acylcarnitines in peripheral blood samples of APAP overdose subjects