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Both are synthesised by the body and available through diet, with supplementation increasingly used for cardiovascular health, mitochondrial disorders, and male fertility

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Furthermore, mitochondrial dysfunction associated with cell apoptosis including membrane potential loss, down-regulation of Bcl-2 and upregulation of Bax and the release of cytochrome c were abrogated in the presence of LC

L-theanine and cystine pretreatment (280 mg/kg for 5 days) could significantly enhance the weight loss and survival rate of rats after the irradiation, which may be connected with the inhibition of apoptosis and the enhancement of the proliferation of bone marrow cells ( In general, L-theanine could induce cancer cell apoptosis through the mitochondrial pathway, inhibiting the EGFR, NF-B, and other signaling pathways, downregulating MMP9, or upregulating Smad2 in cancer treatment