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In addition to being the precursor of norepinephrine, it is also an important neurotransmitter for maintaining the function of extrapyramidal nerves ( In the central nervous system, the main synthesis pathway of DA is from L-tyrosine, which is transformed into L-dopa by tyrosine hydroxylase (TH) and then decarboxylated by aromatic acid decarboxylase (AADC) in the iron and H4-biopterin dependent pathway to produce DA

Then, they get shots weekly for four weeks, and then less often

Detailed information regarding the samples can be found in Supplementary Table S1

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