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doi:10.1093/jn/134.3.489

Some research suggests that individuals who have lost significant weight may experience lower metabolic rates than predicted for their new body size, though this varies considerably between individuals

Double blinding When the researchers administering the experimental treatment are aware of each participants group assignment, they may inadvertently treat those in the control group differently from those in the treatment group

voxel size: 0.45 mm 0.45 mm 4 mm)

Taoufik et al., 2021

On testing cadence, note that there is no universal evidence-based schedule: the frequency of laboratory monitoring should be individualized according to the therapy being used, underlying medical conditions, treatment response, and current clinical guidelines