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Under pathological conditions, abnormal activation or inhibition of mitophagy in cardiac myocytes in heart disease such as myocardial infarction may have a profound effect on cardiac function [60]

Therefore, to include the latter in the S matrix, accumulation reactions were added in the form of sink reactions for phases II and III, and demand reactions for phases I and II ( Figure 1 , step 5)

Adherens junctions are mainly composed of cadherins and nectins, which act mainly on cellular integrity[18]

Additionally, lithium, valproate, and carbamazepine showed neuroprotective effects, preventing reductions in synaptic protein levels induced by cytotoxicity