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Furthermore, ammonia has been observed to activate SREBP-1, thus establishing a feed-forward loop that promotes glutamine metabolism and lipid synthesis, as well as tumor cell proliferation [24]

To overcome this difficulty, modified (strept)avidin or a lower can be made by using biotin that has been modified

10.1016/S0015-0282(99)00462-8

For cells, the timsTOF flex was operated in DDA-PASEF mode