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Ele ativa os genes envolvidos na reparao do DNA, na resposta ao estresse, na remodelao da matriz e nas defesas antioxidantes, ao mesmo tempo que reprime os genes associados inflamao, fibrose e destruio tecidual

Protective role of carbonic anhydrases III and VII in cellular defense mechanisms upon redox unbalance

Cancer cells may become resistant to platinum-based drugs through multiple mechanisms, including an increased ability to repair platinum-induced DNA damage, neutralization of platinum toxicity, and an increase in drug export (38)

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