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These signaling events are commonly assessed using enzyme activity assays, phosphorylation analysis, and gene expression profiling in laboratory systems

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While these diseases have different underlying causes, they share similar pathologies with functional loss of the interconnected vasculature, glia, photoreceptors and RPE, leading to vascular anomalies and photoreceptor death

For long-term storage (months to years), it should be kept in a freezer, ideally below -20C (-4F)