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Moreover, the simulations confirmed that the Cagri P37 had weaker interactions with the ECDs leading to greater uncoupling of the peptide C-terminus from the ECDs (Supplementary Movie 1, Supplementary Tables 4, 5), and parallel increases in the dynamics of the peptide as it engaged with the CTR TM bundle, including F23

Molecules 16 , 20842096 (2011)

Gallbladder-Related Events Cholelithiasis (gallstones) and cholecystitis (gallbladder inflammation) occur at higher rates in semaglutide users compared to placebo

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10.1107/s2052252524007784 102 ChiZ.ChenX.HoltzJ