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Avoid ketorolac use during the third trimester of pregnancy (starting at 30 weeks of gestation) due to the risk of premature closure of the fetal ductus arteriosus and persistent pulmonary hypertension in the neonate (2,3,5,6)

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Normally when one either obtains vitamin B12 from digestion in the stomach or from a low dose oral B12 supplement, a protein called haptocorrin (HC), which is secreted into saliva, binds to the B12 and protects it from acid degradation in the stomach

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2014 Cytoprotective effects against NSAID-induced damage, alcohol lesions, and inflammatory bowel disease models