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those involving the -glutamyl portion of GSH, mediated by -glutamyl transpeptidases, with the rest involving the sulfhydryl moiety, which is responsible for the redox and nucleophilic reactions

Weeks 12 and beyond: Longevity biomarkers

Increased oxidation, impaired GSSG reduction, limited NADPH regeneration, reduced synthesis, and preanalytical artifacts can produce similar changes

Neurol Res 38(4):35863 Lorente L et al (2021) Serum melatonin levels in predicting mortality in patients with severe traumatic brain injury

This area of research is nascent and requires significant further validation

doi: 10.1186/1471-2393-13-72 42 CarsonSAKallenAN