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This process is governed by the angiogenic switch mechanism, where dynamic equilibrium between pro-angiogenic (e.g., VEGF/VEGFR axis) and anti-angiogenic factors (e.g., p53-mediated pathways) determines neovascularization outcomes (95)

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Moreover, it is important to note that TRAb is a specific autoantibody, not typically produced during standard immune responses

[DOI] [PubMed] [Google Scholar] 153.Camaes G., Pastor V., Cerezo M., Garca-Andrade J., Vicedo B., Garca-Agustn P., Flors V.A

The Phase 2 data showed weight loss curves that had not plateaued, meaning longer treatment durations could push the numbers even higher