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Both start at a dose intended to be well below the therapeutic threshold, primarily serving as an acclimation period for the GI system

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Other drugs like octreotide (somatostatin agonist) and bromocriptine (dopamine agonist) can be used to block GH secretion because both somatostatin and dopamine negatively inhibit GHRH-mediated GH release from the anterior pituitary

A second opinion is especially useful when pain in PHN persists despite several medications, when the pain is mistaken for heart, lung, breast, abdominal, dental, or spinal disease, or when procedures are being considered

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