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This pathway can be inhibited by the cell-survival signaling pathways mitogen-activated protein kinase kinase (MEK)/extracellular signal-regulated kinase (ERK) and phosphoinositide 3-kinase (PI3K)/Akt (protein kinase B), which may protect the cells against the cytotoxic effects of VPA [210]

Spermatocyte-specific Gpx4 knockout mice were infertile [85]

doi:10.1002/fsn3.1837

Phylogenetic analysis of arthropod vitellogenins produced several vitellogenin clades reflecting their arthropod taxonomic grouping, i.e., parasitiform ticks and mites, acariform mites, spiders, scorpions, horseshoe crabs, insects, and crustaceans (Fig

PMC 8065891

Moreover, this work explicitly introduces a novel cross-species pharmacokinetic assessment framework, supporting the use of D