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After 2, 4, and 6 days of culture, the cell number in the PDL9 group was significantly lower than that in the PDL3 group (Figure 1C), which indicated that the proliferative ability of senescent chondrocytes was significantly decreased

GHK-Cu reduced inflammatory cell infiltration into lung tissue, increased superoxide dismutase activity (bolstering antioxidant defense in the lungs), and decreased both TNF-alpha and IL-6 production

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Thus, ensuring biodegradability is essential to minimize long-term retention in the body and to enhance the safety and clinical viability of these nanoparticle systems