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For most vaccines, the antibody response is crucial and, thus, the identification of antibodies that can potently neutralize a pathogen is a key factor for accelerating vaccine development

A distinction is made between two nocturnal blood pressure profiles: o reduced dipping, characterized by an average nocturnal BP reduction 18 points has been validated as indicative of a sleep disturbance and warranting an additional diagnostic work-up with vPSG [151]