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Unsaturated VPA metabolites (4-en-VPA and 2, 4-dien-VPA) are potent inducers of microvesicular steatosis in rats, whereas VPA itself failed to induce discernible liver lesions at near lethal doses [60]

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These changes were characterized by either an increase in muscle size and density or a reduction in fat content

The peptide selectively accumulates in the inner mitochondrial membrane where it binds to cardiolipin, a specialized phospholipid essential for organizing electron transport chain supercomplexes and maintaining cristae structure [2][7]

But you should always inform your healthcare provider about all medications and supplements youre using

PMID: 21548867 [2] Chang CH, et al