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To detect expression profiles that spike up periodically at one measured time point, we define a baseline expression level E 0 , plus a burst of expression E at a particular time point , which is analogous to the phase: The Fourier transform for these transcripts does not show a large RP24 or low p-value from our methods

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However, iodine-based CT contrast agents (CAs), routinely used clinically, are inadequate for DECT imaging due to their low K-edge energy (33.2 keV) [7, 8]