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In the 1920s, Otto Warburg observed for the first time that tumors consume more glucose than surrounding normal tissue, leading him to propose the phenomenon of aerobic glycolysis, wherein glucose can be fermented to produce lactate instead of carbon dioxide, even in the presence of oxygen

Molecular and clinical characterization of PTPN2 expression from RNA-seq data of 996 brain gliomas

Notably, their effects extend beyond simple antioxidant activity, through multi-targeted mechanisms, they offer therapeutic approaches for intervening in the E-P-OS network

Harding HP, Novoa I, Zhang Y, Zeng H, Wek R, Schapira M

Furthermore, LDs have been employed as biological lenses to augment the resolution of subcellular structures (microfilaments, microtubules), facilitating the observation of intricate structures within thicker cells, including cancer cells