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In the IPEC-J2 oxidative stress model, we added the Nrf2 pathway inhibitor ML385, which significantly suppressed the upregulation of p-Nrf2 and antioxidant enzyme levels by HT and increased ROS levels

Likewise, Roumeliotis et al

Coral host cells acidify symbiotic algal microenvironment to promote photosynthesis

In vitro-cultured HCT116 cells were treated with mdivi-1 to inhibit DRP1 expression, which resulted in severe chromosome dislocation during mitosis [93]

Additionally, the modified icaritin isopentenyl derivative C3 induces cell apoptosis and cell cycle arrest at S phase in multiple myeloma (RPMI 8226), while another semi-synthetic derivative 11c inhibits the proliferation of liver cancer (Hep G2 and SMMC-7721) cells by inducing cell apoptosis and cell cycle arrest at G0/G1 phase [770, 771]

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