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The l-cystine/glutamate antiporter SLC7A11 introduces cystine from the extracellular environment, which is transferred to the cytoplasm and converted into cysteine through a reduction reaction that consumes NADPH

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Verdel BM, Souverain PC, Egberts ACG, Leufkens HGM

We also assessed for independent association of CC ratio with these outcomes using a MV regression model including age, sex, BMI, and MELD-Na as covariates

V., Kumaraswamy, E., Gladyshev, V

However, since these patients are often deficient in vitamin B12, injectable B12 in the form of hydroxycobalamin is often chosen as part of their treatment