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53 This reveals a novel BCAA metabolism inhibition mode in the context of KRAS inhibition of BCAT2 ubiquitination degradation, explaining the preference for PDAC amino acid metabolism

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In this context, the focus lies not on any direct peptide-to-muscle effect, but on how receptor-driven endocrine signaling remodels downstream muscle biology [6]

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Local overexpression of these genes in the mouse brain resulted in increased anxiety-like behaviour, while local inhibition of glyoxalase 1 expression by RNA interference decreased the anxiety-like behaviour

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