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These dynamic metabolic variations directly influence drug distribution, target expression, and therapeutic response, posing significant challenges to the development of effective personalized treatment strategies [15, 18, 21]

Reduced glutathione in the liver as a potential viability marker in non-heart-beating donors

The unfavorable therapeutic index was likely attributable to a combination of factors rather than a single flaw

WesolowskaABrysJBarbarskaOStromKSzymanska-MajchrzakJKarzelKet al

10.1002/jcp.1041510305 43

Superoxide anion radicals (O 2 . ) are typically the first ROS produced, and its formation is primarily linked to electron transport chains