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Semaglutide and tirzepatide have FDA approved uses, while some other peptides discussed online or in wellness settings are not FDA approved drugs and may involve added safety and regulatory considerations

Effectively, the GSDMD-mediated pyroptosis process promotes the release of mtDNA

One of the primary challenges in incorporating peptides into wound dressings is their inherent chemical and enzymatic instability

Wang et al., 2022), and functional short peptides such as WP9QY (W9) (Zhao et al., 2024b) and PPFLMLLKGSTR (Sun et al., 2024) to form composite hybrid hydrogels that improved the RADA16 hydrogel hydrophilicity and mechanical strength while imparting it with new biological activity

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Finally, although HG106 was recently identified as a SLC7A11 inhibitor (Hu et al., 2020), whether it can act as a FIN remains to be further examined (so far, all other SLC7A11 inhibitors can induce ferroptosis)