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Proteinprotein interactions which support P-gp drug efflux function: P-gp drug efflux function and intercellular transfer has been shown to to be regulated by a number proteins including microtubule, ezrin, radixin, moesin, and CD44

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For peripheral cells, it was shown that ritonavir is itself a substrate of Mrp1 and thereby inhibits the transport of other Mrp1 substrates such as the chemotherapeutic drugs doxorubicin and etoposide [98,99,100,101]

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