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In the light of these findings, the functional plasticity of the intestinal epithelium and its regenerative response to injury are modulated or even controlled by mitochondrial metabolism, supporting the hypothesis that mitochondrial exhaustion contributes to the functional perturbation of the epithelium in IBD (referred to as metabolic injury)

20 and 21c)

And as the weeks go by, youll notice not only a brighter, more even complexion, but also the quiet satisfaction that comes from treating yourself with kindness

In addition, the immune component of the barrier limits access of environmental antigens, while the biological component is maintained through colonization by commensal microbiota 70

Mol Cell Biol (2013) 33:242535

Regulatory mechanisms of aging in aging-associated diseases The hallmarks of aging and aging-related diseases do not exist in isolation