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Particularly in bladder cancer, alterations in mitochondrial dynamics are not only associated with the migratory and invasive abilities of tumor cells but also likely serve as key driving factors for tumor cell metastasis from the primary site to other tissues

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Thus, increased AT1-AA in circulation during pregnancy may activate the CS signaling pathway to generate potent anaphylatoxins, such as C3a and C5a, to induce EOSPE