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doi: 10.1016/j.bbrc.2006.08.066

Yes, though it is rare

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DOSAGE The following dosage recommendations apply unless otherwise prescribed: At the start of treatment, in the first few weeks after diagnosis, 1 ampoule of VITAMIN B12 Depot Panpharma (corresponding to 1000 ug hydroxocobalamin acetate) is administered twice a week

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