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Graphical Abstract Similar content being viewed by others Introduction Gastric ulcer disease (GUD) is a common digestive tract disorder affecting around four million people per year worldwide (Abbasi-Kangevari et al

Acacetin binds specifically to the ATP domain of HSP90, causing HSP90 to detach from COX-2, which leads to COX-2 being ubiquitinated and broken down in macrophages, thereby reducing inflammatory reactions (189)

Coumarins are a class of benzopyrones, consisting of a benzene ring fused to an alpha-pyrone ring, also entailing important effects on human health and promising translational implications [555]

To sustain the genome stability, cells have evolved a complicated fine-tuning mechanism, termed as DNA-damage response (DDR), to detect and repair DNA lesions

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These latter supports help avoid column clogging due to solid contaminants by allowing the creation of a fluidized or expanded bed during sample application [42,50]