Activation of mGlu3 metabotropic glutamate receptors enhances GDNF and GLT-1 formation in the spinal cord and rescues motor neurons in the SOD-1 mouse model of amyotrophic lateral sclerosis
Dynamic expression of autophagy-related factors in autoimmune encephalomyelitis and exploration of curcumin therapy
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Morris, S
Poster Session I - RISK FACTORS - PRIMARY AND SECONDAR PREVENTION 05.00 - RISK FACTORS AND PREVENTION (PRIMARY AND SECONDARY) - 05.02 - SECONDARY PREVENTION P402 - ESOC25-1932 SEX DIFFERENCES IN THE ASSOCIATION BETWEEN C-REACTIVE PROTEIN AND INTERLEUKIN-6 WITH RECURRENT VASCULAR EVENTS AFTER ISCHAEMIC STROKE: AN INDIVIDUAL PARTICIPANT DATA META-ANALYSIS Sarah Gorey 1 , John J McCabe 2 , Katie Harris 3 , Gian Marco De Marchis 4 , Pablo Hervella 5 , Ramn Iglesias-Rey 5 , Mira Katan 6 , Francisco Purroy 7 , Peter Rothwell 8 , Tara Stanne 9 , Yuji Ueno 10 , William Whiteley 11 , Mark Woodward 3 , Cathal Walsh 12 , Peter Kelly 2 1 University College Dublin, Stroke Clinical Trials Network Ireland, Dublin, Ireland, 2 Mater University Hopsital, Stroke Clinical Trials Network Ireland, Dublin, Ireland, 3 The George Institute for Global Health, Sydney, Australia, 4 HOCH Health Ostschweiz, Kantonsspital St.Gallen, St Gallen, Switzerland, 5 Neuroimaging and Biotechnology Laboratory, Clinical Neurosciences Research Laboratory, Heart Research Institute of Santiago de Compostella, Santiago de Compostela, Spain, 6 University Hospital Basel, Basel, Switzerland, 7 Institut Reserca Biomedica, University of Lleida, Lleida, Spain, 8 Wolfson Centre for the Prevention of Stroke and Dementia, University of Oxford, Oxford, United Kingdom, 9 Sahlgrenska Academy, University of Gothenburg, Sahlgrenska University Hospital, Gothenburg, Sweden, 10 Juntendo University School of Medicine, Tokyo, Japan, 11 University of Edinburgh, Edinburgh, United Kingdom, 12 Trinity College Dublin, Stroke Clinical Trials Network Ireland, Dublin, Ireland Background and Aims: C-reactive protein (CRP) and interleukin-6 (IL-6) are independently associated with major adverse cardiovascular events (MACE) after stroke and measurement of biomarkers can improve risk stratification
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