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Acetyl-l-carnitine is able to pass the very selective blood-brain barrier more efficiently than L-carnitine, and therefore play more of a role in brain health

However, the evidence for the efficacy of nutritional interventions alone is less consistent than when combined with other strategies, such as exercise

Figure 5-b

2015;3:e12470

Jaksa Vukojevic, Marija Milavic, Darko Perovic, Spomenko Ilic, Andrea Zemba Cilic, Natasa Duran, Sanja Strbe, Zoran Zoricic, Igor Filipcic, Petrana Brecic, Sven Seiverth, & Predrag Sikiric