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Key benefits of corticosteroids include: Rapid increase in platelet count Effective in managing ITP Flexibility in dosing Intravenous Immunoglobulin (IVIG) Therapy IVIG therapy is a first-line treatment for thrombocytopenia, especially in urgent cases

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Insulin-like growth factor-1 (IGF-1) also activates the PI3K-Akt and Ras-Erk1/2 signaling pathways through binding to receptors, increasing the expression of VEGF to further facilitate the proliferation and migration of ECs [34]

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