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Subsequently, Sies and coworkers evaluated the ability of ebselen to protect intact cells like hepatocytes against iron-ADP-induced lipid peroxidation [75]

Treatment can include a steroid taper starting with methylprednisolone and converting to prednisone over two to six weeks if appropriate

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Myung J, Schmal C, Hong S, Tsukizawa Y, Rose P, Zhang Y, Holtzman MJ, De Schutter E, Herzel H, Bordyugov G, Takumi T

GnRH stimulates the pituitary gland to produce luteinizing hormone (LH) and follicle-stimulating hormone (FSH), both essential for stimulating the gonads to produce sex hormones

ACD occurs in response to environmental perturbations, i.e., any mechanical insult compromising the membrane integrity