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Pharmacol Ther 172 , 2233 (2017)

D., Bell, D., Hall, R., Parry-Strong, A., Docherty, P

67 Adiponectin is secreted by adipose tissue, has a role in regulating energy balance and promotes insulin sensitivity

enrolled 224 HCV-2 and HCV-3 patients, and evaluated PEG-IFN plus RBV administered for 24 weeks and noted higher rates of SVR in HCV-2 patients (93%) than in those with HCV-3 (79%).[53] These results were confirmed in a subsequent meta-analysis: 74% in HCV-2 in comparison with 69% in HCV-3.[54]The presence of steatohepatitis and more advanced fibrosis in HCV-3 could contribute to poorer therapeutic response in these patients.[55, 56] Shah et al

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Role of pannexin-1-P2X7R signaling on cell death and pro-inflammatory mediator expression induced by Clostridioides difficile toxins in enteric glia