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[141] The CDR3 of the light chain and, particularly, the CDR3 of the heavy chain may constitute the most important determinants in antigen binding within the light and heavy chain variable regions

References: Alba, M., Fintini, D., Sagazio, A., Lawrence, B., Castaigne, J

doi: 10.1016/j.jcrc.2014.05.021 43 MicallefJ.SoeiroT.Jonville-BraA