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Therapeutic interventions targeting this axis, such as resveratrol, and quercetin, show promise by simultaneously modulating gut-joint signaling and suppressing ferroptosis, potentially achieving intestinal barrier recovery and chondrocyte rescue

This condition reduces the extracellular and intracellular pH, affects ion homeostasis, leads to membrane depolarization, and intracellular Na + and Ca 2+ accumulation (fig.4)

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This can lead to reduced muscle fatigue and improved recovery process, allowing athletes to train more frequently and with increased intensity

Meyers JM, Munger K

We used onesided t tests when we assumed a normal distribution in which an effect could be measured in one direction