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Nitrone-related therapeutics: potential of NXY-059 for the treatment of acute ischaemic stroke

doi: 10.1159/000486502 47

Since mTOR is located downstream of AMPK and mTOR has been well reported to regulate muscle growth and metabolism 42,43 as well as the eIF4EBP3L as a gatekeeper of mTOR in muscle growth 44 , we next examined the effect of mTOR pathway by measuring the levels of mTOR and eif4ebp3l in the LMNA mutant transgenic fish with or without drug treatment