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As an anti-cancer therapeutic target, several small molecule kinase inhibitors of ERK5 have been reported, and most of them reduce cell proliferation in vitro and tumor growth in xenograft models in vivo [26, 38]

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Apoptosis-inducing Factor (AIF) and Its Family Member Protein, AMID, Are Rotenone-sensitive NADH:Ubiquinone Oxidoreductases (NDH-2)