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Bonilla, E., Medina-Leendertz, S., Mora, M., Vielma, J

Wilson disease: copper-mediated cuproptosis, iron-related ferroptosis, and clinical highlights, with comprehensive and critical analysis update

Recycling of BH2 by DHFR To break the cycle and re-couple eNOS, BH2 must be converted back into active BH4

Causes of deficiency may include a diet low in cysteine and other essential nutrients, increased pollution, excessive alcohol consumption, and certain medical conditions