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Age: Older adults often have a decreased ability to absorb B12

Older adults, vegetarians, vegans, and people with digestive problems that can impede nutrient absorption are at a higher risk of vitamin B12 deficiency and need to supplement

PMID: 29719402

Animal studies have provided evidence that sitagliptin and linagliptin exhibit the ability to attenuate the activity of NLRP3/inflammasome (198)

Fasting glucose and insulin: If you have access to a continuous glucose monitor or regular labs, MOTS-C's effects on insulin sensitivity are measurable

Overall, DMSA therapy in this study seemed relatively safe, with only a few reports of adverse effects that were generally temporary and of mild or moderate severity