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ZDHHC-2 mediates S-palmitoylation of acylglycerol kinase (AGK) in renal clear-cell carcinoma cells, promoting the translocation of AGK to the plasma membrane [232] and activating the PI3K-AKT-mTOR signaling pathway

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Though set guidelines for switching between routes of administration in terms of how to convert dosing are not available to my knowledge, we can use data on pharmacokinetic parameters such as bioavailability to help guide our approximate starting dose selection

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