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The progressive loss of neurons and glial dysfunction following TBI or SCI leads to the formation of cavities within the CNS parenchyma, surrounded by dense glial scars, which hinder functional recovery (217)

Some research has shown that consuming whey protein may support increased glutathione

In summary, these findings suggest that the branches of the tryptophan metabolic pathway (the kynurenine pathway and the 5-HT pathway) may be the mediating links through which the gut-joint axis regulates ferroptosis in OA

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Finally, O 2 radicals can interact with NO radicals to synthesize reactive substances such as peroxynitrite radicals (ONOO) (35, 36)