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Providers should document pain levels, functional limitations, and objective findings like spasm or decreased range of motion

This nuclear localization in elderly Leydig cells correlated with reduced expression of 3-HSD, a crucial enzyme for testosterone synthesis, suggesting a link between nuclear FOXO4 and age-related decline in testosterone production [2]

It is generally avoided in people with iron overload conditions such as hemochromatosis, those with a history of serious reactions to IV iron, and certain active infections and it requires extra caution in pregnancy and some chronic conditions

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