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High dose oral cobalamin may be a suitable alternative in selective cases, where intramuscular injections are not tolerated and compliance is not a problem

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Models of invariant natural killer T cells derived from patient PBMCs also could show that the accumulation of Gb3 negatively affected their numbers and cell function [48], impacting even further on the immune system

10.1073/pnas.1002143107 33 ChangX.ZhuA.LiuF.ZouL.SuL.LiuS.et al (2017)

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