61.3 kda proteins gst glutathione oxidation

61.3 kda proteins gst glutathione oxidation Overexpression of S-Transferases in Human Diseases: Drug Targets and Therapeutic Implications Protein–Polymer Conjugation via Ligand Affinity

Name: 61.3 kda proteins gst glutathione oxidation Overexpression of S-Transferases in Human Diseases: Drug Targets and Therapeutic Implications Protein–Polymer Conjugation via Ligand Affinity
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ProteinPolymer Conjugation via Ligand Affinity and Photoactivation of Glutathione S Transferase Bioconjugate Chemistry Glutathione transferases: substrates, inihibitors and pro drugs in cancer and neurodegenerative diseases Oncogenesis The glutathione system and the related thiol network in Caenorhabditis elegans ScienceDirect S Glutathionylation: From Molecular Mechanisms to Health Outcomes PMC Protein Glutathionylation and Glutaredoxin: Role in Neurodegenerative Diseases The Multifaceted Role of Glutathione S Transferases in Health and Disease

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Description

Gut 62:16251633

Z.FengD

When GSSG accumulates excessively due to dysfunctional SLC33A1 activity, this inhibits enzymes required for proper disulfide bond formation and quality control, resulting in protein misfolding and aggregation within the ER

Vacca et al., 2004

Regulates Blood Sugar Levels Diabetes is both related to insulin resistance and elevated blood glucose, and both of these have the ability to increase oxidative stress